Depression Treatment Zoloft
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Zoloft
Active Ingredients:
- Sertraline
The commercial name of the medication may differ from the brand one. Generic Zoloft manufactured by Thaemo Pharma is available under commercial name Sate.
How does the medication work?
Sertraline hydrochloride belongs to a group of antidepressants called selective serotonin reuptake inhibitors. In clinical doses the medication blocks the reuptake of serotonin in the platelets and increase the amount of serotonin in the synaptic gap. This helps to improve the cooperation between nerve cells and relieve depression symptoms. Sertraline does not possess an affinity to cholinergic, serotonin, dopamine, histamine, adrenergic receptors. The medication also does not increase body weight.
Why is Zoloft prescribed?
Generic Zoloft is used in:
- Treatment and prophylaxis of depressive conditions of different severity accompanied with fear and suicidal attempts.
- Neuropathic and somatoform depression
- Post-traumatic stress disorders
- Obsessive-compulsive disorders
- Treatment of panic disorders accompanied with phobias
- Treatment of nervous anorexia, bulimia and chronic pain syndrome
When Zoloft should not be taken?
You should not take Zoloft if any of the following conditions apply to you:
- Hypersensitivity to any of the medication ingredients
- Epilepsy
- Children under 6 years of age
- Pregnancy
- Breastfeeding
- The medication should be used with caution in: organic disorders of the brain, epilepsy, kidney or liver failure, decreased body weight.
What side effects are possible with the medicine ?
Zoloft may cause the following side effects:
- Digestive system: dry mouth, decreased appetite, dyspepsia, stomach spasms, pancreatitis, hepatitis, jaundice, liver failure.
- Nervous system: drowsiness, headache, dizziness, tremor, insomnia, anxiety, agitation, hypomania, mania, paresthesia, hallucination, psychosis, hyperirritability, tremor, dyskinesia, gait disorders.
- Urogenital system: ejaculation retention, decreased libido, erectile dysfunction, anorgasmia, disorders of the menstrual cycle, gynecomastia, priapism, galactorrhea.
- Sense organs: vision disorders
- Cardiovascular system: increased heart rate, arterial hypertension, edema, faint
- Respiratory system: asphyxia, chest pain
- Laboratory indexes: reversible increase the activity of transaminases, thrombocytopenia, leukopenia, low sodium blood levels.
- Other: nasal bleedings, hypothyroidism, increased sweating, decreased body weight, fatigability, hot flashes.
Sudden cessation the therapy may cause withdrawal symptoms
If any of these side effects occur during the treatment seek medical attention immediately.
This is not a full list of possible Zoloft side effects. If you notice other adverse effects caused by the preparation inform your doctor or pharmacist.
What are possible drug to drug interactions associated with Zoloft?
Zoloft should not be used in combination with:
- MAO inhibitors
- CNS inhibitors
- Alcohol
- Blood thinners (cumarins)
- Antipsychotic drugs (pimozide)
- H2 histamine receptor blockers (cimetidine)
- NSAID's including and Aspirin
- Cardiac glycosides (digoxin)
- Alcohol abuse treatment (disulferam)
- Certain antibiotics (linezolid)
- Lithium preparations
- Other antidepressant including SSRI or SNRI, tricyclic antidepressant
- Narcotic analgesics (Tramadol)
- St.John's wort
- Triptans
- Tryptophan
Let your doctor know if you are taking any of the above mentioned medicines or other preparations including herbals, vitamins and food supplements as they may change the effectiveness or increase the risk of Zoloft side effects.
Additional drug information
The medicines should be kept out of reach and sight of children. You should take the medicine exactly as prescribed by your doctor. Avoid off-label use of the medication. If you are unsure about anything related to Zoloft contact your health care provider or pharmacist. You can also apply to our customer support service.
