Digestive System Omeprazole
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Omeprazole
Active Ingredients:
- Omeprazole
How does the medication work?
Proton pump inhibitor. Inhibit the activity of proton pump in parietal cells of the stomach and thereby blocks the final stage of secretion of hydrochloric acid that leads to reduction of basal and stimulated secretion, regardless of the nature of the stimulus. Due to reduction of acid secretion, reduces or normalizes the effect of acid on the esophagus in patients with reflux esophagitis.
Omeprazole has a bactericidal effect on Helicobacter pylori. Eradication of H. pylori in the combination therapy with omeprazole and antibiotics allows to quickly abort the disease's symptoms, to achieve a high degree of healing of damaged mucosa and persistent long-term remission, and reduce the likelihood of gastrointestinal bleeding.
Why is Omeprazole prescribed?
- acute stomach ulcer and duodenal ulcer (including associated with Helicobacter pylori)
- reflux esophagitis
- Zollinger - Ellison syndrome
- erosive and ulcerative lesions of stomach and duodenum associated with NSAIDs administration
When Omeprazole should not be taken?
- chronic renal failure (including history)
- hypersensitivity to omeprazole
- pregnancy, lactation
- pediatric patients
What side effects are possible with the medicine ?
- digestive system: rare - nausea, diarrhea, constipation, abdominal pain, flatulence
- CNS: rare - headache, dizziness, weakness
- haemopoietic system: very rare - anemia, eosinopenia, neutropenia, thrombocytopenia
- locomotor system: very rare - arthralgia, muscle weakness, myalgia
- allergic reactions: rare - skin rash
If any of these side effects occur during the treatment seek medical attention immediately.
This is not a full list of possible Omeprazole side effects. If you notice other adverse effects caused by the preparation inform your doctor or pharmacist.
What are possible drug to drug interactions associated with Omeprazole?
Omeprazole is known to interact with the following groups of drugs:
- benzodiazepines
- neuromuscular relaxants
- gastroprotective agents
- cardiac glycosides
- alcohol abuse therapy
- antivirals
- antifungal agents
- antibiotics
- anti-tumor drugs
- bronchodilatators
- anti-arrhythmic drugs
- anticonvulsants
- immunosuppressive drugs
Let your doctor know if you are taking any of the above mentioned medicines or other preparations including herbals, vitamins and food supplements as they may change the effectiveness or increase the risk of Omeprazole side effects.
Additional drug information
The medicines should be kept out of reach and sight of children. You should take the medicine exactly as prescribed by your doctor. Avoid off-label use of the medication. If you are unsure about anything related to Omeprazole contact your health care provider or pharmacist. You can also apply to our customer support service.
