Digestive System Ranitidine
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Ranitidine
Active Ingredients:
- Ranitidine
How does the medication work?
Ranitidine is an antiulcer drug. Which works by competitively and reversibly blocking the histamine H2-receptors in parietal cells of gastric mucosa. Suppresses basal and stimulated secretion of hydrochloric acid, increase the the pH of gastric juice. Does not reduce the level of Ca2+ in patients with hypercalcemia. Ranitidine is a weak inhibitor of liver microsomal enzyme system.
Why is Ranitidine prescribed?
Treatment and prevention of:
- stomach ulcer and duodenal ulcer
- NSAID-gastropathy
- heartburn (associated with hyperchlorhydria)
- hypersecretion of gastric juice
- symptomatic gastrointestinal ulcers, erosive esophagitis, reflux esophagitis, Zollinger-Ellison syndrome
- systemic mastocytosis, multiple endocrine adenomatosis
- chronic dyspepsia characterized by epigastric or retrosternal pain associated with eating
- treatment of upper gastrointestinal bleeding
- prevention of recurrence of gastric bleeding in the postoperative period and aspiration of gastric juice in patients who underwent surgery under general anesthesia (Mendelson syndrome)
- aspiration pneumonitis (prevention)
When Ranitidine should not be taken?
- hypersensitivity
- lactation
- with caution: renal and / or hepatic insufficiency, acute porphyria (incl. history), hepatic cirrhosis with portosystemic encephalopathy in history, pediatric patients, pregnancy
What side effects are possible with the medicine ?
- nervous system and sensory organs: headache, fatigue, dizziness, drowsiness, insomnia, vertigo, anxiety, depression, rare - confusion, hallucinations (especially in elderly and debilitated patients), temporary blurred vision, disturbance of eye accommodation
- cardiovascular system and blood (hematopoiesis, hemostasis): arrhythmia, tachycardia / bradycardia, AV block, decreased blood pressure, temporary leukopenia, thrombocytopenia, granulocytopenia
- digestive tract: nausea, vomiting, constipation / diarrhea, abdominal discomfort / pain
- locomotor system: rare - arthralgia, myalgia
- allergic reactions: skin rash, bronchospasm, fever, eosinophilia
If any of these side effects occur during the treatment seek medical attention immediately.
This is not a full list of possible Ranitidine side effects. If you notice other adverse effects caused by the preparation inform your doctor or pharmacist.
What are possible drug to drug interactions associated with Ranitidine?
Ranitidine may interact with the following groups of drugs:
- antacids
- gastroprotective agents
- hypnotics
- beta blockers
- antimycotics
- NSAID's
- narcosis drugs
- hypoglycemic agents
- calcium channels blockers
- drugs that inhibit bone marrow
Nicotine smoking may decrease the effectiveness of Ranitidine. Ranitidine may interact with alcohol.
Let your doctor know if you are taking any of the above mentioned medicines or other preparations including herbals, vitamins and food supplements as they may change the effectiveness or increase the risk of Ranitidine side effects.
Additional drug information
The medicines should be kept out of reach and sight of children. You should take the medicine exactly as prescribed by your doctor. Avoid off-label use of the medication. If you are unsure about anything related to Ranitidine contact your health care provider or pharmacist. You can also apply to our customer support service.
