Epilepsy Neurontin
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Neurontin
Active Ingredients:
- Gabapentin
How does the medication work?
Neuronin contains the active ingredient gabapentin which is structural analogue of GABA. The action mechanism of the medication is different than in preparations which interact with GABA-receptors including valproats, barbiturates, benzodiazepines, inhibitors of GABA-transaminases. Gabapentin works by binding with a2 and subunits of the voltage-dependent calcium channels and inhibits the inflow of calcium ions into the cells. Another action mechanism of the medication is associated with lowering of glutamate-dependent death of the neurons, increase of GABA synthesis, inhibiting the release of MAO neurotransmitters. Gabapentine does not interact with the receptors GABAa and GABAb, benzodiazepine, glutamate, glycine, and NMDA.
Why is Neurontin prescribed?
Neurontin is indicated for the treatment of the following conditions:
- treatment of neuropathic pain in adults over 18 years of age
- monotherapy of partial seizures with secondary generalization or without it in adults and children over 12 years of age
- as additional remedy in the treatment of partial seizures with secondary generalization or without it in children over 3 years of age
When Neurontin should not be taken?
The medication is contraindicated in the treatment of the following conditions:
- Hypersensitivity to any of the medication ingredients
- Children under 3 years of age
- Severe cardiovascular diseases
- Severe liver or kidney diseases
- Pregnancy
- Breastfeeding
What side effects are possible with the medicine ?
- The most common Neurontin side effects include: dizziness, drowsiness, coordination problems, infections, nausea and vomiting, swelling or fluid retention, diarrhea, constipation, dry mouth.
- The less common Neurontin side effects include: depression, hostility, severe dizziness, suicidal thinking or even attempts.
If any of these side effects occur during the treatment seek medical attention immediately.
This is not a full list of possible Neurontin side effects. If you notice other adverse effects caused by the preparation inform your doctor or pharmacist.
What are possible drug to drug interactions associated with Neurontin?
Generic Neurontin may interact with the following drugs and products:
- Alcohol
- Antacids which contain aluminum and magnesium
- Narcotic painkillers (hydrocodone, morphine)
- Non steroidal anti-inflammatory drugs (naproxen)
- H2-histamine receptor blockers (cimetidine)
Let your doctor know if you are taking any of the above mentioned medicines or other preparations including herbals, vitamins and food supplements as they may change the effectiveness or increase the risk of Neurontin side effects.
Additional drug information
The medicines should be kept out of reach and sight of children. You should take the medicine exactly as prescribed by your doctor. Avoid off-label use of the medication. If you are unsure about anything related to Neurontin contact your health care provider or pharmacist. You can also apply to our customer support service.
